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The results demonstrated a significantly higher variation rates in the later passages, when comparing passage 1 against both passage 60 and 120, and comparing passage 60 against passage 120 (one tailed t-test, maximal P = 0.00016).
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A higher variation rate was evident by mapping the transcriptomic reads on the same genomic contigs (Table 5).
Indeed, in grapevine, previous works evidenced a much higher variation rate, with an average of 1 SNP in 47 129 base pairs, according to the genome region and the population studied [ 52, 54, 55].
On the other hand, the effect of the current induced in the earth might require a smaller Pd jump because larger amplitude SCs have higher time variation rate (Araki et al. [2004]) and so the coefficient α for the induction effect might be larger than the usual value 1.5.
This is a five times higher microsatellite variation rate compared to the other two individuals (0.3%) in this study, which cannot be attributed to experimental variations for the total number of microsatellite loci called were similar across all samples.
A targeted survey of some of the most frequent CNVs known by 2006 (TSPY array, AZFc region and Yq heterochromatin) confirmed the high levels of variation and high mutation rates at these loci in samples chosen to represent diverse branches of the Y-chromosomal phylogeny (Repping et al. 2006).
The high time variation rate of this SC is interesting also as a space weather event.
However, he exhibits a very high nsSNVs variation rate (8.4×10−6 bp−1 year−1) when referenced to his own previous genomic state.
However, even well-trained experts may have high inter-observer variation rates, so computer-aided diagnosis (CAD) is necessary to help radiologists in detecting and classifying breast cancer [ 22].
Birkmeyer et al. found that for Medicare patients in 1995, lower extremity revascularization, carotid endarterectomy, back surgery, and radical prostatectomy rates had particularly high variations, and coronary artery bypass grafting (CABG), transurethral prostatectomy, mastectomy, and total hip replacement also had high variation in rates across regions [ 5].
In addition to phase variation, high mutation rate and homologous recombination [ 7, 8], the R-M system diversity has been proposed to contribute to the genetic variation of the bacteria [ 9, 10].
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