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Higher scores signified higher study quality.
The scale ranges from 0 to 9 points, with higher points indicating higher study quality.
Scores are awarded out of 9 possible points, with higher scores indicating higher study quality.
Methodological analysis indicated a trend for higher study quality with serum studies as compared to tissue-based investigations.
There are a substantial number of reports that higher study quality is associated with lower estimates of treatment effects [ 15- 19].
Prospective studies reported statistically significant higher study quality scores (median (IQR) 6(5–7)) than retrospective studies (3(3–5); p<0.05).
Similar(49)
Nine points on the NOS reflect the highest study quality.
Studies with a total score of 8 were considered to show the highest study quality, whereas a zero score indicated the lowest quality.
As a consequence, a majority quality score as rated by each systematic review was used as a unified rating of highest study quality.
High study quality was related to a high journal impact factor for p53 (P=0.010), but not for EGFR (P=0.59) and HER-2/neu (P=0.65).
It assesses studies of all levels of evidence, with a focus on high study quality, to provide recommendations for clinical practice and guide further research.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com