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A drug might have a larger total number of adverse events reported for several reasons unrelated to safety, including more widespread clinical use, a higher reporting rate, the patient population treated, and more extensive international sales by the pharmaceutical sponsor.
The proportional reporting ratio takes into account two possibilities: a) that wider use or a higher reporting rate exposes a drug to a greater chance of having a violence case attributed, and b) that a higher number of reports might have occurred by chance.
Significant differences were found but these were not systematic, i.e. one abattoir had a significant higher reporting rate in Danish Red, but a similar rate in Danish Holsteins.
Moreover, Thomas et al. added, in 2004, that women might be more likely to seek medical advice, thereby causing higher reporting rate [ 32].
Except for Moroccan, Turkish, other non-Western EM and first-generation EM, women had a higher reporting rate of STI-related episodes than men (Fig. 3).
Aboriginal persons in Taiwan were more likely to have TB caused by M. bovis and had a 5-fold higher reporting rate for TB (9) than nonaboriginal persons.
Similar(51)
33– 37Additionally, higher reporting rates have been documented with the use of an enhanced surveillance system.
In theory, higher reporting rates in urban areas could reflect greater propensity for person-to-person transmission; however, this is more commonly seen with organisms with human reservoirs.
The opposite seemed to occur in 2011 to 2013, when the questions were the other way around — those data showed a higher reported rate of children with developmental delays, and a lower rate of ASD.
But, the highest reporting rate of PMUs in China is 100 Hz, which cannot meet the Shannon sampling theorem.
However, the high availability rate of journal publications in our sample did not correspond to a high reporting rate of study data, which is consistent with previous findings.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com