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Current studies with moderate examination periods up to 5 years reported that higher plaque accumulation and gingival inflammation were associated with the absence of KM [25,26].
Human studies with substantially smaller cohorts confirm these results and reported even higher plaque scores at implant sites in the absence of KM [7,25,26,30,36,37] On the other hand, several longitudinal studies revealed no significant association between higher plaque scores and KM level [11,23,38,39].
In a study done by Eliades et al. [4], it was seen that stainless steel represented the highest critical surface tension and energy and can be expected to have higher plaque retaining capacity.
A retrospective study, based on 339 implants, showed that a lack of keratinized tissue around dental implants, especially in the posterior region, led to higher plaque accumulation and mucositis [4].
Interestingly, higher plaque compaction could reduce the Abeta pathology [ 33].
Additionally, higher plaque neutralization levels (e.g., 90% vs. 50%) have demonstrated less sensitivity [ 6].
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(The best seller at this event was a one-meter-high plaque of pure salt from the Taoudenni mine in Mali, which went to a European collector for more than $4,000 — see, someone is crazier than you).
His cholesterol was through the roof, he was at risk for heart disease and he had high plaque buildup in his arteries.
The regions that were affected first consistently maintained their lead over the regions that became affected later, i.e. the anterior neocortex and the subiculum always showed the highest plaque densities.
In humans, high plaque levels can lead to heart attacks and strokes.
Possibly, this study population presented a rather high plaque concentration in hippocampus, resulting in high glial BDNF reactivity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com