The highest number of datasets were found to contribute data in the Pacific NE (n = 72), followed closely by the Atlantic central-west (CW; n = 69); regions with the least number of datasets (n = 3 for each region) were the Arctic, Atlantic southwest (SW), Atlantic-Antarctic, and Pacific-Antarctic.
The quality of the evidence was high for the association with colorectal cancer (high number of datasets and events, narrow CIs, and low heterogeneity), moderate for liver cancer, and low for bladder cancer.
We performed different imputation models, including (1) a higher number of imputed datasets, m=120, (2) only exposure and outcome variables and (3) more covariates than in the main imputation model.
To analyze the performance of the algorithms, considering datasets with a higher number of directly connected bnodes, we developed an RDF dataset generator, based on that included in the Berlin SPARQL Benchmark (BSBM) [24].
We observe slightly higher results for Twitter links, and we note that this may be a result of the higher number of Twitter links in our dataset or as a result of the greater difficulty of the inverse task.
Interestingly, kinases from outlier group 1 share a much higher number of active compounds within the dataset (85.77) as compared to kinases from kinase outlier group 2 (12.03) and few shared activities have been found to be one of the limitations of analyses such as the one performed here (see main text for details).
Since the train and test datasets have higher number of 'benign' instances, benign traffic is naturally classified with much higher accuracy.
Another interesting characteristic of the mouse-rat dataset is the higher number of false positives, roughly doubled that of the human-mouse or human-rat dataset for all the methods.
A slightly higher number of self-links in the yeast coAP/MS dataset compared to the combined yeast Y2H dataset argues for the former explanation.
Interestingly, a higher number of DArTs align to the maize EST dataset (1226) than to the sorghum (978) EST dataset, even though sorghum is generally thought to be a much closer relative to sugarcane [[ 25]].
