Available experimental data on columns subjected to bidirectional forces indicate that higher levels of damage and a higher loss of ductility and strength have been observed compared to similar tests under unidirectional shear forces.
Fields with higher proportions of orchard grass showed higher levels of grazing damage; and damage was lower in years when abundant alternative feeding areas (AFAs) in the form of unharvested potatoes were available.
The BRCA carriers of mutations, with no overt sign of cancer, nevertheless had significantly higher levels of DNA damage than the controls.
Consistent with morphological parameters of antitumor activity, we observed higher levels of oxidative damage product accumulation in primary tumor tissue of mice treated with NPs (Fig. 6).
Support for this hypothesis comes from observations of higher levels of oxidative damage in the DNA of WBC of cancer patients compared with healthy controls.
Dobutamine is related to higher levels of cardiac damage and higher doses of dobutamine interfere with the responsiveness of the baroreceptor.
Consistent with this, they also reported higher levels of DNA damage in the form of DNA single strand breaks and BaP-DNA adducts in S-enriched cultures.
Normal ductal mammary epithelium is only one to two cell layers in thickness and would be subject to much higher levels of RNA damage than large areas of MA captured by UV.
Results showed that, following corrections for experimental error, those patients whose PBLs demonstrated higher levels of DNA damage following 10 h of SN-38 exposure ex vivo had significantly longer times to progression than those with lower damage levels (median 291 vs. 173 days, P = 0.014).
Expression of Progerin induced higher levels of DNA damage and mitochondrial reactive oxygen species in dopaminergic neurons derived from PD patients, which enabled the detection of PD-associated disease phenotypes such as dendrite degeneration, mitochondrial enlargement, Lewy body precursor inclusions and suppression of tyrosine hydroxylase expression (Miller et al, 2013).
Flow cytometry analysis showed that BSO induced more than two times the amount of γH2AX staining, which demonstrated higher levels of DNA damage after cisplatin exposure in the presence of BSO.
