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Grid analysis provides a higher level of specificity to weather patterns compared to the broad, low precision county level analysis previously conducted by multiple governmental and state agencies (e.g. FEMA 2002, 2008; NCDC 2013).
This newly emerging strategy, which is thought to yield a higher level of specificity than conventional ATP analog inhibitors, may lead to the development of a different class of inhibitors that could be used either alone or in combination with available catalytic inhibitors to achieve increased drug efficacy.
In the same vein, while intersections of computational approaches may achieve a higher level of specificity, they also generally achieve a much reduced sensitivity [32].
Here we introduce a new more highly validated allelic discrimination assay, referred to as BurkDiff, to provide a higher level of specificity for accurate identification of B. pseudomallei and B. mallei and simultaneous differentiation when necessary.
Blocking or competitive ELISAs have been shown to be especially useful where a higher level of specificity is required.
In order to address this, we moved our comparisons further along the ontology to provide a higher level of specificity.
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While assays focusing on plasmid targets allow for a high level of specificity, a specific chromosomal target for detection of avirulent and plasmid-cured B. anthracis strains is needed.
In this way IAMs may be used indirectly to generate policy insights with higher levels of specificity and confidence.
In addition, a reiterative process of PWM optimization and selection of rationally informed cut-offs based on newly discovered and validated sRNAs may allow for progressively higher levels of specificity without excessive loss of sensitivity.
10, 11 We found that a number of sign and symptom combinations could provide higher levels of specificity for cholera surveillance in Haiti.
23 The Malawian study found considerably lower sensitivity for women's reports of being in a relationship, where an age disparity greater than 5 years was only 24.3%, compared to 79.6% here, but similar or higher levels of specificity.
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