Immunoblotting detection revealed significantly higher levels (median rate 10.3, P≤0.005, Student's t-test) of Egr-1 expression in all wasted patients with pancreatic cancer compared with controls.
When levels were examined according to menopausal status, no difference was observed between postmenopausal cases and controls, whereas premenopausal cases had higher levels (median, 13.9 nmol l−1) than their matched controls (10.9 nmol l−1, P=0.01).
Workers who no longer worked at the plant had much higher levels (median, 75) than did nonworkers (median, 24) but lower levels than those who continued working there (median, 148), consistent with a gradual excretion of PFOA from the body after ending high exposure.
About 51% of NSI isolates produced low levels of p24 antigen (median, 142 pg/ml) in monocyte-derived macrophages (MDMs), 31% produced medium levels (median, 1584 pg/ml), and 17% produced high levels (median, 81,548 pg/ml) (p < 0.001).
Strikingly however, the LUAT-associated coding genes are expressed at high levels (median expression value 3.9 FPKM; Figure 1E).
Patients with low RRM1 mRNA expression levels had significantly longer median survival than those with high levels (median, 13.7 vs 3.6 months; P=0.009).
The median TTP time for patients with low levels of MMP-11 was not significantly different from patients with high levels (median = 6.0, range from 4.98 to 7.02 months vs. median = 5.0 months, range from 3.28 to 6.72 months; P = 0.178, Figure 2).
Malignant mucinous cysts that included high-grade dysplastic lesions, however, expressed a significantly higher AREG level (median 986 pg/ml) compared to benign mucinous cysts (median 63 pg/ml) and non-mucinous cysts (median 85 pg/ml).
They reported that patients with a lower gene expression level of CDA showed significant longer overall survival than those with a higher expression level (median, 8.5 vs 3.7 months; P=0.03).
Depending on the treatment of uncertainties, recent seismic hazard maps are developed for multi-levels of confidence, including high confidence level (median level or 50th percentile) and low confidence level (median plus one standard deviation level or 84th percentile).
