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The folklore said higher doses produced greater effects.
Some women with severe symptoms need higher doses.
The water-soluble version could be given in higher doses.
The pills are essentially birth control pills in higher doses.
Food and Drug Administration officials asked for more data on higher doses of Crestor.
At higher doses, it even reversed the accumulation of plaque in mice.
In higher doses, it can paralyze the respiratory system and cause death.
"Physicians have experimented with higher and higher doses," Mr. Pyott says.
Higher doses produced stronger reactions at the injection site, but none were serious.
"And my suspicion is that higher doses, if effective at all, would be of marginal benefit".
But men often have thicker skin and stronger muscles, doctors say, and frequently require higher doses.
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