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The cluster has an average information content of 2.68 (bits), which denotes higher conservation in the sequence of these fragments.
Moreover, PUF motifs as well as surrounding sequences exhibit higher conservation in PUM bound messages as opposed to transcripts that were not found to be associated, suggesting that PUM function may be modulated by other factors that bind conserved elements.
Moreover, known phosphosites showed higher conservation in most phosphomotifs than in all of the STY residues.
We also find higher conservation in the arrangement of ESEs in constitutive exons compared to alternative ones.
On the other hand, the chromosomal integron, which occupies approximately 3% of their genomes, shows higher conservation in ANI between species than any other region of their genomes.
Furthermore, there was higher conservation in the 3′ UTR of each HOX gene than in the 5′ UTR, similar to previous findings [ 24].
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We further investigated the reasons of higher conservations in first introns by testing their association with various regulatory marks, and the associations of conservation and regulatory signals in first introns with the gene's expression level.
As observed in the other three plant species, PtPIPs have the highest conservation in which all 17 positions are 100% group conserved (Additional file 8).
As a set of sequences with high conservation in eutherian mammals, we used the UCSC phastCons28wayPlacMammal most conserved sequences (PCSs).
The amino acid residues in the WD40 repeat region involved in the interface show high conservation in other vertebrates, but not in starfish (Fig. 8a).
The ADAM metallopeptidase domain 17 (ADAM17 or TACE) and its close relative ADAM10 are two of the most important ADAM members that share high conservation in sequence, structure and function, but exhibit subtle difference in regulation of downstream cell signaling events.
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CEO of Professional Science Editing for Scientists @ prosciediting.com