Along with this, higher amounts of mutant huntingtin protein from the total extract and isolated mitochondria from brain tissues of HD transgenic mice co-immunoprecipitated with GAPDH relative to the samples from wild-type mice (Fig 4B).
For this, all available operators in μJava tool were selected with the aim of generating the highest amount of mutants (fault) as possible.
The higher amount of xanthan produced by this mutant may be explained by a mechanism of compensation for the lack of adherence, though it is not enough by itself to promote the formation of the biofilm, suggesting that the xanthan required for biofilm formation may be maintained in the extracellular matrix in an adhesin-dependent manner.
The results indicated that the Δphx1 mutant accumulated higher amount of ROS than the wild type during stationary phase (60, 72 h culture time), when Δphx1 mutant cells still retain full viability in minimal media [ 15].
The higher amount of EPS observed in XacFhaB mutants may be attributed to the adaptation of this regulatory pathway.
The lack of beta-oxidation leads to higher amount of stored fat in nhr-49 mutant worms, as seen in nhr-49 ok2165 nhr-49 ok2165d S10Figs
Interestingly, the E224Q mutant had a higher amount of Cdt1 bound than the wild type or Cdc6-NQ complex, as reported for a Cdc6-E224G mutant (Randell et al., 2006; Fernandez-Cid et al., 2013), suggesting build up of an intermediate Cdt1-containing compriorprior to dhMCM (double hexamer MCM) loading.
The Δgox mutants produced higher amount of malic acid and citric acid compared with the parental and wild-type strains, and after 7 days of cultivation, production of oxalic acid was also observed in the Δgox mutants.
On the contrary, 39E7 mutant showed a higher amount of carotenoids in November, but no significant statistical differences were observed with respect to the parental in January.
There was a higher amount of GTP-KRAS in HSC45 and SH101P4 cells, which carried amplified mutant KRAS, than in MKN1 cells, in which the level of GTP-KRAS was comparable to AGS cells, which carried non-amplified mutant KRAS.
