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18F-SKI249380 is a PDGFR-selective tracer, which demonstrates improved delivery to PDGFB-driven high-grade gliomas and facilitates treatment planning when coupled with nanoformulations and quantitative PET imaging approaches.
These data suggest that immunoliposomal nanocontainers based on antibodies against GFAP and the E2 extracellular fragment of connexin 43 are suitable for targeted delivery of diagnostic and therapeutic drugs to the peritumoral invasion zone of high-grade gliomas.
Further prospective randomised trials are also warranted to accurately determine whether the delivery of radiotherapy immediately after HBO could be beneficial for patients with high-grade gliomas.
You have high-grade generators and high-grade skepticism.
China has chiefly high-grade coal reserves.
No high-grade deposits are known.
"Twenty years of high-grade, maybe.
A1 TROUBLING RAMIFICATIONS: The discovery of high-grade anthrax spores suggests that somewhere, someone has access to germ weapons with the potential to inflict huge casualties if the right delivery system is used, experts said.
High-grade dysplasia in Barrett's esophagus.
It was a high-grade military performance.
High-grade surface osteosarcoma.
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