Sentence examples similar to high-dose led from inspiring English sources
The agency's decision is similar to the findings in May of a federal advisory panel, which concluded that lower doses of the drug were safe and effective, but expressed concern that higher doses led to daytime drowsiness and other side effects.
However, the high dose led to facial weakness with high risk in our study.
Higher doses led to a major decrease in the swelling (~200 and ~100 gwater/ggel at 20 and 40 kGy, respectively), resulted by the higher crosslink density.
The lowest dose led to 100% survival, whereas the highest dose led to 12.5% (i.p).
In unpublished work we have found that higher doses led to fetal abnormalities.
Hipk1MO2 caused identical phenotypes to Hipk1MO1 at doses between 8 32 nanograms per embryo; higher doses led to significant lethality (Supplemental Table S2 and data not shown).
While a high dose led to unintentional increase of intracranial pressure and decrease of coronary perfusion pressure, a low dose did not affect intracranial pressure and was associated with mild increase of coronary perfusion pressure during cardiac arrest.
Low doses of cerulenin caused cell cycle arrest, whereas higher doses led to cytotoxicity.
Ybarra et al 7 concluded that the toxicity of cobalt at a higher dose led to death.
The dosage of pilocarpine was lower than the dose used for animals without EEG electrodes because we found that higher doses led to mortality.
In the MV4-11 model, pacritinib dose-dependently blocked tumor growth and the highest dose led to complete tumor regression in all mice.
