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There is a possibility that ZIKV outbreak may emerge again in the future, especially in high vector concentration areas.
However, high vector doses were required and the presence of pre-existing neutralizing antibodies precluded a number of patients from participation.
The epidemiological patterns of these viruses suggest that Zika virus could cause other outbreaks, particularly in tropical regions with high vector concentration.
This behavior has been attributed to several reasons including the susceptibility of humans and the mosquito vectors of the virus- conditions facilitating mosquito breeding result in high vector density and ability of the vector to efficiently transmit the virus [1, 4, 5].
In both low and high vector concentrations, PBA stimulated an approximate 2-fold increase in normalized reporter activity (Figure 10C).
Bangladesh has very high vector species diversity and vectors suited to these habitats may be responsible for the observed results.
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The more frequently a cluster appears, the higher vector dimension is allocated.
Among the resulting clusters, the more frequently a cluster occurred, the higher vector dimension it will be assigned.
This procedure guarantees that these clusters are rather well-separated Gaussians, in particular for higher vector dimensions.
At higher vector doses, greater than 1 ng/ml of plasma insulin was produced, completely reversing nonfasting hyperglycemia in treated rats.
Retinal histopathology indicated that traumatic lesions from the injection were common, but thinning within the injection region occurred only at the two highest vector doses.
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