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Column breakthrough studies demonstrated that the dynamic adsorption capacity of FF-PEI-R440 was much higher than the other three resins at flow rates higher than 30 cm/h because of its high uptake rate.
It was found that the modified nanocarriers showed reasonably high drug load efficiency for CPT and a high uptake rate by cancer cells overexpressing EGFR through clathrin-mediated endocytosis.
The interrelation suggests that tailoring only one design parameter may not be effective to achieve high uptake rate.
Our model also predicts that, optimally several tens of ligands should be coated onto the NP surface in order to achieve high uptake rate.
Results showed that Mini-B had a substantial binding (association) affinity for both DEPN-8 and DPPC based on a high uptake rate constant (kon) and a low dissociation rate constant (koff) (Table 2).
Thus, scanning human tumors with positron emission tomography (PET) [17] has verified that a high uptake rate of glucose constitutes a hallmark in cancer cells, presumably required to confer adaptive advantages when facing acidic and hypoxic environments [19].
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Although microorganisms within biocrusts fix N, biocrusts may also exhibit high uptake rates of NH4+ when active.
The distinct metabolic and physiological characteristics of thermophiles, including broad substrate range and high uptake rates, coupled with recent advances in genetic tool development, present unique opportunities for strain engineering.
Liver and kidneys had high uptake rates of BM.
However, such dependency does not exist at high uptake rates as the carbon nutrients become saturated.
Vaccination programs often organize subsidies and public relations in order to obtain high uptake rates and coverage.
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