Sentence examples for high tolerability of from inspiring English sources

This recommendation was largely based on the high tolerability of BoNT-A and the safety concerns related to opioids, despite the fact that effectiveness and the bulk of evidence favoring opioids, particularly oxycodone and morphine, is far more robust [10].

The high tolerability of this formulation during years 1 and 2 was maintained during year 3; 5.5% of patients withdrew from treatment because of adverse events in the final year.

The high tolerability of PARP1 for small molecules appended to 2H-phthalazin-1-one resulted in a number of high affinity binders in our small molecule library, the best representative of which, [124/131I]-I2-PARPi, was tested as a PET and SPECT tracer.

Cancer immunotherapy using protein-based therapeutics such as EGF-MAP will require repetitive administration, and thus the relatively high tolerability of CFPs make them superior to classical ITs.

The rationale for the combination of gemcitabine plus mitoxantrone was the therapeutic efficacy, the low systemic toxicity and the high tolerability of both drugs.

Thus, tolerance to MTX therapy may be used as a surrogate measure for potential high tolerability of anti-TNF treatments in clinical practice.

These three factors may indicate more severe clinical symptoms and a higher tolerability of drug treatments.

A very high safety ratio and an absence of interaction with other mechanisms involved in blood pressure regulation, together with initial evidence of high tolerability and efficacy in hypertensive patients, indicate Rostafuroxin as the first example of a new class of antihypertensive agents designed to antagonize adducin and EO-hypertensive mechanisms.

In light of our evolving knowledge of the immunological mechanisms of some of the newer therapies for MS, there appears to be a need for the development of treatment algorithms to help physicians decide on the most effective treatment pathway from the earliest stage of MS, so that patients can benefit from high efficacy, high tolerability treatments throughout the course of their disease.

Because of its high tolerability, also susceptible regions come into question for topical therapy.

From a clinical perspective these results are relevant also in view of ALC high tolerability profile which could allow to employ the drug in patient subpopulations who are sensitive to the side effects associated with classical monoaminergic antidepressants.