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The first, generally called the exposome, is based on high throughput technological measures of exogenous exposure biomarkers at a single point (or multiple points) in time.
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The Bioplex suspension array thus proves to be a reliable, cost-effective and high-throughput technological platform for genotyping.
Therefore, there is a need to develop a reliable, cost-effective and high-throughput technological platform for genotyping markers involved in the aetiology of variable response to drug therapy or disease pathologies.
Acknowledging this limitation, recent high-throughput technological advances have revolutionized the way in which the immune system can be explored after vaccination and has prompted an increasingly pervasive doctrinal shift from reductionist to holistic or 'systems biology' research [ 2].
As is the case for microarrays and other high-throughput technologies, data from new high-throughput sequencing technologies are subject to technological and biological biases and systematic errors that can impact downstream analyses.
Therefore, fabrication of such structures at low cost and with high throughput is a huge technological challenge.
Recent technological advances in high throughput, deep sequencing for the human genomes and proteomic technologies to comprehensively characterize the human proteomes in conjunction with multiplexed targeted proteomic assays to measure panels of proteins involved in biologically relevant pathways have made significant progress in understanding cancer at the molecular level.
Technological advances in high throughput genome sequencing are making whole genome sequencing (WGS) available as a routine tool for bacterial typing.
Especially since 2005, the development and application of next generation sequencing (NGS) technology, characterized by its low cost and high throughput through massively parallel sequencing, displays an unprecedented technological breakthrough in biology, medicine and many related fields.
Recent technological advances allow for high throughput 16s rDNA sequencing of the microbial community found on the human skin [26], [27], [28], [29].
Technological development is essential for high throughput, high precision and low cost data generation [ 5].
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