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This paper presents an investigation about non-specific protein adsorption that was found to occur on the membrane disks used in a commercially available high throughput device.
In most experiments, high throughput device is favored by most researches as it allows a given sample to be analyzed within the short time This parameter is typically reported as either the volumetric flow or number of cells processed per second.
Meanwhile, Phylos of Lexington, Massachusetts, has developed "combinatorial" methods and a unique tagging system to churn out proteins for doing protein-protein analysis on other makers' chips.But for all the promise shown by the various approaches, researchers in the field have little experience with such high-throughput devices.
Many scientific experiments produce large amounts of data using high-throughput devices.
This strategy is homogeneous, easy operation, enzyme-free, isothermal, and can be easily adapted to high-throughput devices without the need of designing complicated instruments.
In this review, I summarize the current knowledge in the field and discuss how nanopore probe techniques will provide a new generation of research tools in nanomedicine for quantitatively examining the details of complex recognition and, furthermore, will represent a crucial step in designing other pore-based nanostructures and high-throughput devices for molecular biomedical diagnosis.
The findings suggest that the first principles and empirical methods provide a useful guide for high-throughput device design.
To address these issues, we have developed a high-throughput device called Microplate-based Enrichment Device Used for the Selection of Aptamers (MEDUSA).
Thus, in this work we report a high-throughput device that has great potential to overcome shortcomings of current AD diagnosis by identification of an AD-specific phenotype in a single analytical step.
Strong and growing interest has consequently been shown in solution-based processes (e.g. ink-jet[ 3a] or gravure printing[ 3b-d] or slot-die coating[ 3e]) to address these limitations and achieve the ultimate potential of plastic electronics in large-area, low-cost, high-throughput device fabrication.
Due to the small feature sizes required for our optomechanical devices, we have chosen to use foundry-based nanofabrication, which provides high throughput of devices with a minimum feature size of 100 nm using top-down DUV photolithography [29].
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