Exact(2)
High throughput adaptation and chemical sensitization.
Digital DNaseI footprinting is a high throughput adaptation of classical DNaseI footprinting [ 1].
Similar(58)
Here, we evaluate a simple, cost-effective, high-throughput adaptation of the PRT method to determine gene copy number using the pyrosequencing technique to quantify sequence differences between the test and reference PRT amplicons [42], [51], [52], and compare this pyrosequencing PRT (PPRT) with the published triplex PRT [53] method and real-time QPCR.
Models which are amenable to routine use and high-throughput adaptation are particularly desirable in the context of industrial drug discovery.
The high-throughput adaptation of the liquid co-culture assay could facilitate the screening of large libraries for the identification of mutants or compounds that block the synthesis or activity of AHLs.
The approach is also feasible and amenable to adaptation for high throughput screening of drug candidates.
This section will focus on the types of assays used in small-scale academic laboratories, but adaptation to high throughput and multiplexed methods are now also essential for translational drug discovery.
Because of its simplicity, effectiveness, specificity, and easy adaptation to high throughput, this technology holds enormous scientific, commercial, and therapeutic potential.
This straightforward approach with its potential for automation and adaptation for high throughput applications may be of interest in all cases where morphological differences are difficult to determine and the experience of a professional taxonomist is presently needed for species identification.
Adaptation of modern high throughput methods [ 276] might help to get a clearer picture of the microscopic basis of cell elasticity.
At the same time it assesses rooting depth using a new high throughput method that sheds light on potential adaptation mechanisms for drought that should prove useful in breeding programmes.
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