Interestingly, RAD21 expression also lost its prognostic significance in microsatellite instability high and CpG island methylator phenotype high subsets of tumours, but maintained significance in the p53-positive group.
Together, this work implicates a role for TOX3 in tumor progression/metastasis as well as modulation of ER-dependent responses, potentially explaining the poorer outcome of the TOX3-high subset of LumB breast cancers.
To address this objective, we designed an Illumina GoldenGate SNP assay from a high quality subset of the SNPs discovered in 20 diverse O. sativa landraces by the OryzaSNP project [11].
The first approach used a reference map constructed using either an alternative marker system or a high quality subset of GBS markers (henceforth, bin-mapping approach).
No significant differences in Ki67 labelling index were demonstrated in the low vs high MKI subset of NTs, the only difference being confined to the MYCN amplified tumours.
The high quality subset of protein-coding sequences selected to integrate the Trinity assembly, as described in the methods section, comprised 48,846 sequences.
This is caused by infection with the high risk subset of HPV types, of which HPV-16 is the most important, being responsible for over 60% of global cervical cancer cases [ 2].
The FDIC, the government arm that insures depositor money in commercial banks, has offered consumers an assessment of the payday loan industry in general, which it calls a "high risk subset of sub prime lending".
For this study, we identified a high-quality subset of introns and IGRs for which homology could be inferred with high probability (see Methods).
The Department Of Health said the price requested by the maker, Gilead Sciences, was far too high and it was not feasible to limit the drug to a smaller, high-risk subset of the whole "at risk" population.
