Sentence examples for high specificity analysis from inspiring English sources
We compared results from (a) a low paralog specificity analysis that included all probes on the microarray, including ones that cross hybridize to both paralogs, (b) a medium paralog specificity analysis that excluded probes whose sequences cross-hybridized to both paralogs, and (c) a high specificity analysis that excluded probes having up to three mismatches with a nontarget paralog.
In high-specificity analysis where methylation of both the PPP1R3C and EFHD1 genes was regarded as methylation, specificity improved to as high as 96% while sensitivity was 53%.
IT-based tools exhibit high specificity for analysis of splicing neutral variants in hereditary breast/ovarian cancer and other disorders.
Similar proportions were recovered in the high paralog specificity analysis (results not shown).
The high paralog specificity analysis excluded probes that perfectly matched both paralogs and also those that had up to and including three mismatches with the non-target paralog.
Despite its high specificity, our meta-analysis shows that BRAFV600E mutation analysis has a low sensitivity in diagnosing papillary thyroid cancer in thyroid nodules.
Furthermore, a specific conformation of the bound β2GPI as a single molecule or of a β2GPI layer could minimize the binding of aD4 5 and, thus, bring about the high specificity of aPG analysis.
The simultaneous application of differently labelled antibodies against tumour cells and normal cells secures a high specificity of the analysis.
DNA methylation in the SHOX2 locus was previously used to reliably detect lung cancer in a group of critical controls, including 'cytologically negative' samples with no visible tumor cell content, at a high specificity based on the analysis of bronchial lavage samples.
Initial validation analysis confirmed high specificity and sensitivity of the method.
ROC curve analysis confirms high specificity and sensitivity of the ability of urinary α1-ACT measurement to discriminate sCJD status.
