Sequencing datasets of nucleosome positions in different human cell types (CD4+ T cells, CD8+ T cells and granulocytes) and in vitro, generated by high-throughput SOLiD technology, were analyzed [ 33].
Apple, which a decade ago had enviously high profit margins and a solid technology lead, subsequently started multiple operating system development projects and even entered into an alliance with I.B.M. based on one of the projects, known as Pink -- an effort that collapsed under its own technological and bureaucratic weight.
On the firm level, it is important that firms have multiple projects and product portfolios, high ability to adapt, and solid technology platforms.
These technologies include the Roche/454 platform [ 27], the Illumina/Solexa system [ 28], and the ABI SOLiD technology [ 29], all of which have high-accuracy, high-speed, and low-cost compared with first-generation sequencing technology (Sanger sequencing).
Few places in the world are more chaotic than Israel, where stocks sell for an average of 16 times estimated 2003 profits and some solid technology companies trade way below recent highs.
SOLiD technology is well-suited for resequencing studies as it returns high volumes of data and the sequence-by-ligation strategy is able to distinguish sequencing errors from true nucleotide variants during alignment [ 47, 48].
Although, to date, the SOLiD technology has not been used in studies on ancient DNA, it offers an important asset i.e. high accuracy in base calling due to its two-base encoding sequencing strategy.
NetLogic's customers suggest solid technology and strong future growth.
The SOLiD technology has built-in error-detection and correction.
High-throughput DNA sequencing was carried out at the National Laboratory of Genomics for Biodiversity (CINVESTAV, Irapuato, Mexico) using the Roche/454 system for PaMx73 [ 14], and the SOLiD technology for H70 DNAs.
