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For this purpose well-designed multicenter studies are desirable to achieve a high sample size.
According to central limit theorem, regarding high sample size, sample mean have normal distribution so we can use t-test.
Mean (± 1 standard error of the mean, as black arrows) are shown, but standard error of the mean are narrower than symbol widths because of high sample size.
We then use classical estimation theory to determine the theoretically exact biases and errors inherent in photoclinometric surface slope and show when they may be approximated by asymptotic expressions for sufficiently high sample size.
Further studies with high sample size may lead us to uncover the pathogenesis of EGS and to increase the sensitivity and applicability of in vitro techniques as diagnostic tools.
The high sample size coupled with the long time series, offers an indication of the effect of tree-ring age, tree-ring width and local climate on wood density of European beech, and highlights as well the high variability between individual trees.
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"Because Registered Reports set high methodological standards, for example requiring high sample sizes and statistical power, researchers can find that their experiments take longer to conduct than they otherwise would under the status quo," Chambers writes.
However, we believe that an experiment with high sample sizes is necessary in order to better support this claim and to better understand how familiar places contribute to the integration process of multimedia learning.
Correct model selection is a considerable challenge in the association mapping context, even in cases with relatively high sample sizes.
This prompted for instance high sample sizes at the Baltic Sea coast and at Lake Constance in reaction to outbreaks in these locations.
It may be that the advantages of IBD mapping would be realized for very high sample sizes.
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