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We need to identify the 7 million people who are at high risk of type 2 diabetes so that we can give them the lifestyle advice and support they need to prevent it.
The NICE guidance seeks to help identify people at high risk of Type 2 diabetes.
The included studies suffered from several limitations and high risk of Type I and II error.
To develop and evaluate a simple tool, using data collected in a rural Chinese general practice, to identify those at high risk of Type 2 diabetes (T2DM) and prediabetes (PDM).
Increased insulin concentration is a surrogate for insulin resistance and early assessment of fasting insulin may help in identifying those who are potentially at high risk of type 2 diabetes, hypertension, and cardiovascular disease.
The conclusion of the principal investigators in this study: "Lifestyle intervention in people at high risk of Type 2 diabetes induces sustaining lifestyle change and results in long-term prevention of progression to Type 2 diabetes".
However, it is difficult to compare data from a longitudinal intervention study with individuals at high risk of type 2 diabetes describing the effect of the certain genotype on the weight development and a cross-sectional study carried out in a different population.
Identifying individuals with high risk of type 2 diabetes is important.
A1C has been proposed as a new indicator for high risk of type 2 diabetes.
South Asian migrants are at particularly high risk of type 2 diabetes.
Most individuals at high risk of type 2 diabetes intend to and attempt to change their lifestyle (1– 3).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com