The methodology is applied to obtain broadband excitation that is not only tolerant to RF inhomogeneity typical of high resolution probes, but is relatively insensitive to relaxation effects for T1 and T2 equal to the pulse length.
The method they developed, Electronic REference To access In vivo Concentrations (ERETIC), uses either a broad band antenna [3], [4] or the second coil in a high resolution probe [5] [7] to broadcast an amplitude modulated signal that replicates a free induction decay (FID).
Of the large-scale approaches available to study biological diversity, next-generation sequencing technology allows a deep and high-resolution probing of differences among groups or individuals in a species [10] but is too far removed from the level of proteins to provide much functional insight into the adaptations.
The broadest utility of aCGH is obtained by enabling flexible and high-resolution probing of regions of interest while preserving the greatest possible complexity of targets derived from whole genome samples.
"A high-resolution probe could reveal them early in their development".
But in the first decade of 20th century new high-resolution probes tremendously improved this technique.
Multiscale endoscopy platforms that use widefield imaging are needed to better direct the placement of high-resolution probes.
A prototype 2.5-mm 1H high-resolution probe for an 18.8-T (800 MHz) nuclear magnetic resonance spectrometer has been designed, together with a dedicated amplifier capable of delivering up to 1 kW of power.
The achievement of a microminiaturized electrostatic electron optical column with very-high-resolution probe beam is an important challenge in the fields of electron beam lithography, metrology, and inspection for semiconductor and/or display devices.
We have chosen an elementary example to illustrate the capabilities of the optimal control formalism: broadband, constant phase excitation which tolerates miscalibration of RF power and variations in RF homogeneity relevant for standard high-resolution probes.
The new type of high-resolution probe described in this study provides site-specific reporting of protease activity and insights into mechanisms by which cells migrate through extracellular matrices; it also helps to clarify discrepancies between previous studies regarding the contributions of proteases to metastasis.
