One additional complication for field validation efforts using these high resolution predictions are the current technological limitations of survey vehicles and equipment (i.e. ROVs, submersibles, drop cameras, etc).
The COG assignment yields a higher resolution prediction of the molecular function than a gene family assignment derived from PFAM.
phastCons elements are smaller and more numerous (1,395 elements averaging 6.7 bp in length) than mitoPopCons elements (33 elements averaging 167 bp), perhaps implying that phylogenetic data allow for higher resolution prediction than even our dense polymorphism data.
Kelvin K. Droegemeier, a professor of meteorology at the University of Oklahoma and an expert in high-resolution prediction, also warned of the problems that can occur when the initial estimates that form the basis for forecasts are wrong.
The high-resolution prediction of protein protein docking can now create structures with atomic-level accuracy.
Because these processes act at different spatial scales, multi-scale approaches are required not only to detect the patterns of soil distribution but also to develop generic and high-resolution prediction models for the characterisation of large areas.
Again, there was one model (1cqkA) with a high-resolution prediction, as presented in Figure 2g.
This result suggests that as whole-genome sequencing becomes more ubiquitous, it may become possible to perform such high-resolution prediction in the nuclear genome as well.
In the future a more generic solution to overcome this obstracle might be to using high-resolution prediction method such as K-mers to assign a genuine reference genome.
However, what we have provided here is not a high-resolution prediction machine, but a typical representative of an early-phase model where the experimental data allows the construction of a tentative model, but does not permit extensive confirmation of underlying premises and parameter values.
