Nonetheless, based on the higher resolution analytical approach, i.e., bisulfite sequencing, which was capable of revealing methylation change of any single cytosine within the analyzed region, we have found that, for both analyzed loci, all three types of cytosine methylation patterns, CG, CHG and CHH, underwent changes due to the etoposide treatment.
Compared with the cultivation-based techniques, PCR-DGGE and 16S rDNA sequencing offer comprehensive and high-resolution analytical advantageous means to investigate the bacterial communities (Dong and Reddy 2010).
Multi-cycle bending deformation of an individual boron nitride (BN) nanotube is performed inside a 300 kV high-resolution analytical transmission electron microscope (TEM) using a piezo-driven scanning tunneling microscope (STM TEM holder.
High-resolution analytical techniques showed oxidation to take place at and immediately ahead of the tip of an open crack, forming a closed but layered oxide structure about the prior (now oxidized) grain boundary.
Atomic structures of single-crystalline iron-based nanowires crystallized inside multi-walled carbon nanotubes during pyrolysis on silicon substrates with ferrocene as a precursor were analyzed using high-resolution analytical transmission electron microscopy and electron diffraction.
Applying high-resolution analytical techniques, the natural and man-made environmental conditions promoting unwanted carbonate scaling, corrosion, and fragmentation are evaluated comparable to scientific approaches in paleoenvironmental (paleoclimate) studies based on mineral precipitates (e.g., Boch et al. 2011; Dietzel et al. 2015).
Full physical characterisation of solid materials is now made possible with the help of high-resolution analytical techniques (infrared spectroscopy, powder X-ray diffraction, thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC)) on the molecular, particulate and bulk levels (Pifferi et al. 1999).
Advances in materials processing has enabled the fabrication of tailored structures and morphologies offering, at times, orders of magnitude improvements in sensitivity, while high-resolution analytical methods have enabled a much improved examination of the structure and chemistry of these materials.
We characterized the microstructure, chemical composition and resulting local mechanical properties of the enameloid from teeth of Isurus oxyrinchus (shortfin mako shark) by performing an in-depth analysis using various high-resolution analytical techniques, including scanning electron microscopy, qualitative energy-dispersive X-ray spectroscopy and nanoindentation.
Nevertheless, the two high-resolution analytical techniques, Fourier transform ion cyclotron resonance mass spectrometry (FT ICR MS)[ 8] and NMR spectroscopy,[ 6b, 9] which are essential in this endeavor, have serious shortcomings: MS only provides molecular formulae, and standard 2D or 3D NMR experiments cannot deliver the structures of individual compounds contained in complex mixtures.
