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High resolution analyses of flaked stone artefact technology coupled with palaeoecological reconstruction from oxygen isotope analyses of freshwater shells from two rockshelter in the highlands of Northwest Thailand are described.
High resolution analyses of δ13CTOC values, maize pollen concentrations, and mineral influx were conducted on sediments deposited during a ∼220 year period of prehistoric maize agriculture in the watershed of Laguna Castilla, a small lake in the mid-elevations of the Cordillera Central, Dominican Republic.
Early applications focused mostly on the analysis of human skeletal tissues as a way to reconstruct major shifts in human diet, but current stable isotopic approaches have expanded to include high resolution analyses of human, animal, and plant remains, which are helping to better define the resource exploitation and management strategies that underscore changes in the human diet.
Overall, our protocol allows obtaining accurate and reproducible morphometric measurements that reveal subtle variations of the morphological signature, and the short duration (1.8 hours) of the whole analytical process renders high resolution analyses of ash shape achievable for volcano surveillance applications.
High resolution analyses of these data, such as the one shown in Figure 4, with Xist sequences from additional species may allow researchers to pinpoint other slowly evolving regions that may be important for general Xist function, and perhaps to identify candidate regions for L1 involvement in XCI.
For all species found in the high resolution analyses, CAD/ETD MS/MS data were manually interpreted for sequence validation and PTM localization.
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Hirose et al. (2017) show much higher resolution analyses including smaller island features and even a land large river contrast over the Amazon River.
Further methodological optimization will likely enable higher resolution analyses.
This demonstrates a capacity for higher resolution analyses when using the HD chip.
Higher resolution analyses of selected regions of recurrent genomic abnormality on chromosome 20, using array CGH and FISH, suggest the coordinate amplification of several genes that play a role in breast cancer evolution.
From our data, this may be a reasonable approximation for a low/medium resolution level in terms of anchor points per Mb of the genome; however, in higher resolution analyses, small inversions may completely change the picture, leading to a variable number of breakpoints depending on the particular history of the genera being compared.
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