Sentence examples for high rates of replication from inspiring English sources

Moreover, the ubiquity of defective interfering particles with small genomes and high rates of replication [42] suggests that replicative fitness and genome size are linked for many viruses.

Under suboptimal therapy, the combination of both the high rates of replication and mutation leads to the emergence of drug resistance.

HCV infection is considered a chronic liver disease, likely resulting from immune evasion by HCV quasi-species generated from high rates of replication errors (Farazi and DePinho, 2006).

Chk1 has been demonstrated to be important for replication origin firing, high rates of replication fork progression and replication fork stabilization [ 34, 54, 55]].

Bacteria are especially prone to mutation because their genome consists of a single chromosome and because they have a high rate of replication.

These comparisons revealed a relatively high rate of replication of the previous findings in GHS.

Inactivation of MMR causes a high rate of replication errors resulting in an elevated frequency of mutations.

Unfortunately, the high rate of replication combined with the high mutability of the virus leads to the rapid emergence of drug-resistant strains efficiently undermining the efforts to stop the AIDS pandemic.

Hepatocytes in foci or islands of altered cells (putatively preneoplastic) show higher rates of replication than normal liver cells; various different liver tumor promoters cause a further increase of proliferation of focal cells.

Early preneoplastic foci grow slowly without promotion, despite the relatively high rates of cell replication.

In chronic HCV infection, high rates of viral replication are often associated with progressive liver fibrosis.