While a second, allele-aware alignment increases accuracy at predicted heterozygous sites, these modest gains, still accompanied by a high rate of false discovery, require an additional alignment.
This produces incorrect read alignments and leads to a high rate of spurious variant calls.
The result is a high rate of gaps and indels that cause problems for most multiple sequence alignment ("MSA") techniques, including the popular Clustal X [16].
Also, check your wheel alignment if you hit a major pothole or curb at a high rate of speed.
The previously high rate of emigration declined.
Deoxyribonucleic acid analysis and multiple sequence alignment suggest that both P proteins may maintain their structural function in the ribosomal stalk, in spite of the high rate of mutations detected.
ITS sequences are not as widely used as other rDNA regions and protein-coding genes for higher-level phylogenetic inference due to the high rates of evolution of the region; ITS alignments are typically difficult to extend beyond the genus or subfamily level [19].
high rates of home ownership.
Maniema province records high rates of malnutrition.
Consistent with high rates of sequence evolution, our divergence analysis revealed a very limited number of conserved sites across group A and group B alignments (fig. 6).
This can be improved by optimizing the alignment algorithm to tolerate a higher rate of errors and especially more indels.
