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Complexity of the decision was categorized into subgroups by consensus between three researchers (LG, IH, PT): low (open trial or randomized trial without blinding), or high (randomized trial with either the use of placebo, or blinding, or both).
This might trigger the emergence of mechanisms to halt the high randomized sampling of the sequence spaces.
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Clinicians should take the advantage of China's large population, rich case source, broad disease spectrum, and low cost to conduct high quality randomized clinical trials.
Evidence may also be weak because a small patient population makes it difficult to conduct high quality randomized clinical trials.
This review highlights the need for further high quality randomized clinical trials to establish the relationship between systematic pain assessment and clinical outcomes in different ICU patients populations.
Thus, our findings may be based on hypoglycemic episodes of moderate to high severity; randomized trials with prespecified protocols and intensive follow-up may produce higher absolute risks for hypoglycemic events.
There is a great deal of evidence from high quality randomized clinical trials and systematic reviews on the efficacy of a wide range of interventions in relation to the care of preterm babies [ 7, 10].
In this survival meta-analysis, we used novel methods to determine quantitative pooled estimates of the time lags to benefit for breast and colorectal cancer screening, based on data from high quality, randomized clinical trials.
The authors cast a wide net, pooling data from high-quality randomized trials conducted over the past few decades as well as single case reports of injuries.
In the 1980s, a high-quality, randomized trial in Finland found that children who chewed xylitol-sweetened gum had as much as 60 percent fewer cavities compared with children who didn't.
How would you have felt — after over a decade of following your doctor's advice — to learn that high-quality randomized trials of these standard practices had only just been completed?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com