Exact(1)
To minimize the amount of poor quality sequence in the chromosome representations and to better automate future builds, we developed the concept of "high quality overlap regions" (HQORs).
Similar(59)
The high quality overlapping expressed sequence tags (ESTs) were assembled into 46,584 putative transcripts, and more than 700 SSRs and 92,000 SNPs/InDels were characterised.
We paired PhrapUMD with the UMD Overlapper [11], which corrects errors in the reads and accurately computes a set of high-quality overlaps that we call "reliable".
Although there was some variation in the odds ratios observed, the confidence intervals of the pooled effects from each of the analyses of high quality trials overlapped with the confidence intervals of the pooled odds with all of the trials.
Although the results of the sensitivity analyses found some variation in the ORs observed, the confidence intervals (CIs) of the pooled effects from each of the analyses of high quality trials overlapped with the CI of the pooled odds of all trials.
Amplifying large fragments of mtDNA that overlap from high quality genomic DNA or samples enriched for mtDNA are a good way of detecting organellar DNA.
The outputs of the Newbler assembly contained in ASGARD include 'isotigs' (continuous paths through a given set of contigs, named 'isotigXXXXX' where XXXXX is a five-digit unique numeric identifier) and 'singletons' (high quality single reads lacking significant overlap with any other read, named with a 14-character unique identifier).
The overlap between the high quality regions mapped by the control- and glioma-reads totalled 9.5 Mb, equal to 90% of the control-mapped regions; the correlation in read coverage between control and glioma reads was high, with r = 0.958; the density distributions of the control and glioma reads along different chromosomes were also highly correlated, with r = 0.957.
To compare minipig tissue expression profiles to their human counterparts, we used a high quality human microarray dataset with 13 overlapping tissues and 16,032 shared genes [ 30].
Sequences containing more than 100 bp after quality and vector trimming were regarded as high quality sequences, which were then assembled by CAP3 software using default settings (overlap length cutoff > 30 and overlap percent identity cutoff > 75) [ 63].
Upon examination of high quality mate pairs and linear reads, read depth spikes of coverage where BACs overlap were apparent.
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