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This typically results in high-quality concealment, even though it may sound robotic and buzzy during events of high packet loss.
Further trials are warranted and should be of high quality, including concealment of allocation, appropriate unit of randomisation, selection of placebo, blinding of outcome assessments and minimisation of losses to follow-up.
The RCT procedures match those of high quality trials with randomization and allocation concealment, blinding of patients and clinical staff [ 36].
Although allocation concealment was considered high quality for 22 of the 45 trials (it was unclear for 16 and poor for 7), the overall assessment of the risk of bias was considered as low for only 12 studies.
We counted a summary score for "yes" answers and considered studies as of high quality if they had adequate randomization and group allocation concealment, similar prognostic factors at baseline and a described and acceptable drop-out rate.
Was assigned a grade of "A" (high quality) in the following methodology domains: random-sequence generation, concealment of allocation, and selective outcome reporting; assigned a grade of "C" (unknown) in the following methodology domain: blinding.
We labelled a trial as high quality if it was rated as adequate for randomisation and allocation concealment plus either blinding or loss to follow-up under 20%.
Fifty four of the included trials were rated as high quality in terms of random sequence generation; the corresponding numbers were 24 for allocation concealment; 70 for blinding of outcome assessment; 95 for incomplete outcome data; and 127 for selective reporting.
High quality?
Open Processes Encourage High Quality.
Young people want high quality.
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