Sentence examples for high quality alignment from inspiring English sources
The purpose of this study was to create and validate an aligner with the goal of quickly generating a high quality alignment and having the flexibility to use any reference alignment.
This strategy allowed us to make a high quality alignment for the first ∼1075 aa, and the last ∼500 aa.
However, all taxonomic groups are monophyletic in the STAP alignment based tree (Figure S3), suggesting that a high quality alignment might make up for poor species sampling.
Using the simple nearest alignment space termination algorithm, the resulting aligner operates in linear time, requires a small memory footprint, and generates a high quality alignment.
Also, the AU plots (Figure 1b) suggest that the common removal of signal peptides [17], [18], [19], [20] may not be necessary, since these areas still possess high quality alignment blocks.
Hence we did not remove areas of uncertain alignment, especially since the AU plots of both the Solenopsis and Apis BAli-Phy alignments suggest that there are still high quality alignment blocks within these "problematic" areas to warrant their inclusion in the overall alignment procedure (Figure 1b).
Moreover, it produces high quality alignments consistently when aligning large number of sequences, i.e. Kalign2 is well suited for MSA tasks in large-scale genome analysis.
Scaffolding alignments are selected from the remaining high quality alignments (i.e., more than one in silico map aligns to the same consensus genome map (Fig. 3 d)).
For the sake of obtaining high quality alignments, we used a structure-based sequence alignment server, FUGUE [29], to align our collected sequences.
We have used a new alignment benchmark to investigate whether MSA programs are capable of constructing high quality alignments for the sequences resulting from modern biotechnologies.
Most of our problems were inherent in attempting to generate high quality alignments of short sequences that are only distantly related to known ss-rRNA genes.
