Sentence examples for high priority candidates from inspiring English sources
In conjunction with the observed high non-synonymous natural variation within the global 3k genomes pool, it makes them high priority candidates worthy of further investigation.
Our analyses support these as high priority candidates for therapeutic evaluation in DLBCL alongside PD1 blockade.
Findings in these species suggest HD-Zip genes as high priority candidates for crop improvement.
Among those, we highlight a predicted subtilisin inhibitor, a xylanase, a duplicated gene of unknown function and three toxin mimics as high priority candidates for functional studies.
Supporting the notion that miR SNPs are high priority candidates for functional consequence we show that 22% of SNPs falling within validated MRESSs have reported associations related to a disease phenotype or risk.
As adaptive genetic variants have been driven to higher frequencies by environmental factors (i.e, positive selection), SNPs showing high FST values may be considered high priority candidates for association studies for gene by environment studies.
In this review, we use a cross-species cross-platform analysis to consider all available published rodent microarray data and novel human RNAseq data in order to provide high priority candidate genes for consideration in future DA studies.
qPXO79_6-1 spanned 4 spannedross 148 kb at 21.4 Mb and included a Putative SNPsne Cacrosspeptidase (LOC_Os06g36570) and an ABC transporter (LOC_Os06g36650) as high priority candidate genes.
The objectives of forming this consortium were (i) to pool expertise for selection of both loci and SNPs; (ii) to reduce costs by producing a standardized genotyping platform; and (iii) to facilitate cross cohort meta-analyses for a large set of SNPs in high priority candidate loci.
We postulate that CNV-miRNAs are potential functional variants and should be considered high priority candidate variants in genotype-phenotype association studies.
With relevance to human disease we show that publicly available resources can be used to identify high priority candidate SNPs for functional studies.
