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Many areas of the world experience a high population burden of metabolic abnormalities collectively known as metabolic syndrome (1).
Chronic exposure to ambient PM2.5 is linked to increased morbidity and mortality in many epidemiological studies and results in high population burden, making it a large public health concern.
To our knowledge, this is the first study to report the high population burden of sapovirus, which may partly be due to emergence of a novel sapovirus strain during the study.
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For the world as a whole, it was demonstrated that TTH resulted in a higher population burden (approximately 55% of total burden) than migraine (45%).
The observation that the highest population burden of PFOA was found in the Little Hocking Water Association district is consistent with water quality measurement reports from the affected water districts [many of which are publically available; also see Supplemental Material, Note 2 (doi:10.1289/ehp.0800379.S1)].
We had limited statistical power to evaluate the predictive effect of individual R variants, however both our previous study [ 15] and a meta-analysis [ 14] attributed the R151C variant with the highest population burden based on prevalence and relative risk of melanoma.
Fourth, our approach to developing high impact indicators prioritised those associated with higher population burdens of illness.
Transmission prevention is accorded a high priority in Bangladesh for two reasons: the high respiratory disease burden and high population density.
Breast cancer and leukaemia receive a relatively higher research spend than the population burden of these cancers, and the spending on leukaemia is quite extreme.
The positions of breast cancer and leukaemia to the right of the figure indicate a relatively higher research spend than the population burden of these cancers, and the relative spending on leukaemia is quite extreme.
High population density may be an additional burden.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com