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Fifty-two patients (83.9%) included in this study had a high plasma concentration in oxacillin or cloxacillin (Fig. 1).
One possible way to overcome the above issue is to use infusion instead of bolus injection (upon fully determining the PK/PD) to allow better dissolution of the nanoparticles, where recently, a successful use of nanoparticles to deliver drugs to high plasma concentration was reported [32].
AA-amyloidosis is a consequence of a chronic inflammatory disease with persistently high plasma concentration of SAA.
Mediastinal adenopathy was associated with an advanced age and a high plasma concentration of BNP.
Thickening of interlobular septa was associated with a low cardiac index and high plasma concentration of BNP.
The production of milk appears to be blocked by the high plasma concentration of progesterone during pregnancy [ 37- 40].
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Abnormally high plasma concentrations of amantadine may elicit symptoms of neurotoxicity and cause seizures and coma.
Moribund gummy sharks had very high plasma concentrations of lactate and potassium.
Our ability to show an association between higher omega-3 index and improved insulin sensitivity is likely due to the relatively high plasma concentrations of n-3 PUFA observed in our participants.
In mice deficient in succinic semialdehyde dehydrogenase, high plasma concentrations of 4-hydroxybutyrate result in high concentrations of 4-hydroxy-4-phospho-butyryl-CoA in brain and liver.
High plasma concentrations of albuterol were observed in both asthma and COPD patients presenting to the emergency department.
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