Sentence examples for high pathology from inspiring English sources

The data supported previous findings from a study investigating neuropathologic and biochemical differences in the oldest old, which evaluated nondemented pathological aging (referred to as high pathology controls) [ 3].

While increasingly recognized, there is a range of terms for pathological aging that makes review of the literature challenging, including presymptomatic or incipient AD [ 4], preclinical AD [ 6], pathological AD [ 7], nondemented high pathology controls [ 3], asymptomatic persons with AD neuropathology [ 10], intermediate probability mismatches [ 11], and pathologically preclinical AD [ 5].

Post-mortem analysis in human subjects disclosed that Aβ(1 40) rather than Aβ(1 42), whether in soluble or in insoluble form, discriminated more readily between AD patients and high pathology controls [8].

This engagement of the complement system has not been observed in the brains of high pathology controls, contributing to evidence of the involvement of acute mediators in AD.

Fifth, high pathology controls (individuals who have Aβ and tau aggregates at levels similar to AD patients, but do not develop dementia) show lower signs of inflammation [ 41].

Finally, to validate expression of UNC13C, we performed in situ hybridization on tissue from three additional human hippocampi showing no, moderate, and high pathology according to Braak and Braak staging.

Correlational analyses demonstrated a further pattern of group differences by which higher pathology scores were associated with higher slow spindle densities and slower spindle frequencies for the Nightmare but not the Control group.

Ultrasound examinations of Achilles tendon in 298 participants identified a higher pathology rate among men than women (17/127, 13%, versus 8/171, 5%).

Strong perinuclear and nuclear staining was common and more widespread in the higher pathology grades compared to normal.

Staining of cells in the submucosa was also seen more frequently in the higher pathology grades (severe dysplasia/CIS and carcinoma) compared to normal.

The increase in cIAP-2/BIRC3 staining occurred at a higher pathology grade than the grade at which phospho-Akt staining increased (mild/moderate dysplasias) or p65/RELA nuclear localization was increased (moderate dysplasia).