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Dkk-1 levels at baseline were increased both in the study population compared to the control groups and in the MM patients with high of bone disease compared to all other groups [ 119].
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Osteitis fibrosa is characterized by high serum PTH, high resorption and high turnover of bone, and may produce skeletal softening and/or deformation.
T scores of ICTP, fDPD and BAL tended to be higher at higher grades of bone metastasis.
There are also animal welfare issues: "there's a high incidence of cannibalism in cage-free systems, and also high incidence of bone breakage," he says.
These observations may be consistent with a higher level of macrophage recruitment as part of clearing the high amount of bone debris observed peri-implant.
They added, however, that the high incidence of bone fractures, which often lead to fatal complications in the elderly, were troublesome.
High doses of bone morphogenetic protein-2 (BMP-2) are required for effective bone regeneration.
Several studies reported a high rate of bone resorption after insertion of implants in bone augmented ridges [4, 5].
Ameloblastoma has a high risk of bone invasion and local recurrence.
Renal transplant recipients (RTR) suffer high rates of bone loss and increased risk of fracture.
DC is a rare progressive congenital disorder with characteristics of high rates of bone marrow failure, pulmonary fibrosis, oral leukoplakia, nail dystrophy, abnormal skin pigmentation, etc.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com