Sentence examples for high mutation tolerance from inspiring English sources

Detection of caliciviruses requires high mutation tolerance and throughput.

Mutations that impair replication [You et al., 2004], translation initiation [Tang et al., 1999], and splicing [Abbink and Berkhout, 2008] have also been described in RNA viruses that typically have a very high mutation tolerance.

It could be deduced by mathematical modeling that cancers with CIN differ from cancers with MIN with respect to their tolerance of high mutation rates.

Wheat is especially well suited for TILLING because of the tolerance of recently evolved polyploid species to high mutation densities [ 36].

Higher site entropies indicate a higher inherent mutational tolerance.

high mutation frequencies.

Finally, we use our results to show that HA's antigenic sites are disproportionately tolerant of mutations, suggesting that a high inherent tolerance for mutations at key positions targeted by the immune system is one factor that contributes to influenza's antigenic evolvability.

A high tolerance mutation reduces the killing rate of the whole population.

The fact that such antigenic mutations fix at high frequency implies some degree of mutational tolerance at antigenic sites, since no mutations would fix if these sites were under absolute structural or functional constraint.

The foregoing results show that the antigenic sites in HA have an unusually high inherent tolerance for mutations.

We show that hemagglutinin has a high inherent tolerance for mutations at antigenic sites, suggesting that this is one factor contributing to influenza's antigenic evolution.