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The quality scores of NHL studies ranged from nine to 12 points, which indicate a high methodology quality.
Studies were considered to be of high methodology quality if at least seven out of 10 quality criteria were respected [ 25].
Significant heterogeneity was present in most of the pooled analyses, but was markedly reduced when analyses were restricted to study reports with high methodology quality scores.
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For example, both Brown A [ 22] and Thomas O's [ 23] study have found that trials with industry funding had a higher methodology score than those with public funding.
Bearing in mind that most promising candidates have to be tested in hundreds or even thousands of samples, validation requires quantitative, robust, (multiplex) and high throughput methodology.
The high throughput methodology identified human-derived scFv with EC50 ranging from 5.0 – 110.9nM.
A high quality methodology will be used in keeping with CONSORT guidelines.
In contrast to high throughput methodology for the analysis of DNA, RNA, and proteins, current strategies for metabolite characterization still face significant obstacles.
The main strength of our trial lies in the high level methodology used to evaluate the structural effect of ASU-E in hip OA.
This success highly motivates our EAPCN team to maintain a platform for neuropsychiatric publications comprising high class methodology in the European catchment area.
A high-resolution methodology is proposed.
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