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One of the known limitations for biosensor assays is the high limit of detection for target cells within complex samples (e.g., Escherichia coli at 104 to 105 CFU/mL) due to poor capture efficiencies.
This may well be the consequence of the concentrations to be expected in cord blood and the relatively high limit of detection, 0.5 μg/L [54].
Fig. 6 The low and high limit of optimal balloon volumes that provide accurate measurement during both end-expiratory and end-inspiratory occlusion.
The V MIN and V MAX both satisfying the two phases were defined as the low and the high limit of the optimal balloon volume range.
For example, a low limit and a high limit of 0 and 1.5 × 105 counts, respectively, are used for Fig. 1.
The ensemble, 7·Hg2+ upon interaction with different class of anions showed high affinity for cyanide with ∼16 fold fluorescence enhancement and high limit of detection, 1.25 μM.
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As the correlation was poor with very high limits of agreements, it is unlikely that increasing the number of patients would have significantly modified the results.
Potentiometric sensors are typically unable to carry out on-site monitoring of environmental drug contaminants because of their high limits of detection (LODs).
Most of the earlier methods are not ideal since they are time-consuming, have high limits of detections, use of surplus organic solvents, strenuous sample preparation, involve expensive instrumentation and long chromatographic run times.
Furthermore, it has high limits of detection (LOD) when compared with other methods and a spatial resolution limit of ∼0.5 mm at best.
Preliminary data by Malbrain and colleagues indicated unacceptable high limits of agreement of different invasive CCO measurements in 10 patients with IAH [ 17].
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