Sentence examples for high levels of target from inspiring English sources

Here we report the development of a class of structurally versatile cationic lipopolyamines designed specifically for delivery of siRNA which show high levels of target transcript knockdown in a range of cell types in vitro.

We also discuss how the production of high levels of target terpene compounds can be achieved in fruits by the expression of individual or a combination of (i) the MEP or mevalonic acid pathway enzymes, (ii) prenyltransferases, and/or (iii) terpene synthases.

Adenovirus-mediated gene therapy holds potential for many diseases, but especially for applications requiring high levels of target tissue transduction.

Overall we have demonstrated very high levels of target organ damage among workers with hypertension in urban Ghana associated with poor control of hypertension.

Furthermore, when cytolytic activity was examined in dLNs and spleens of tumor-bearing mice, we observed high levels of target cell lysis even by day 2 after T cell transfer.

In support of this conclusion, experiments in which ITC and IVC assays were performed simultaneously in tumor-bearing mice showed that within the same animal, minimal target lysis occurred in tumors at day 2 post-T cell transfer even while high levels of target lysis were observed in dLNs and spleens (LAN, unpublished observations).

Due to their biological function and high level of target specificity, these enzymes are under intense investigation as tools for gene targeting.

The ability to produce a high level of target gene knockdown in the lung with minimal toxicity demonstrates the potential of these lipopolyamines for use in developing RNAi therapeutics for pulmonary disease.

The vectors permit a high level of target expression in E.coli and are mostly derivatives of pET47b (PSPCm2, PSTCm8, PSTCm10 PSPCm11, PSPCm11, NSKn1).

To investigate whether this small number of pulses is sufficient to induce higher levels of target gene expression, protein levels of a p53 target gene (Xp) induced by oscillatory and non-oscillatory p53 are compared at 1200 min (this time period corresponds to 3 to 4 pulseslses).

Reisolation of virus was attempted for all tissues; tissues from which virus was recovered generally were those with the highest levels of target genes.