Ovarian cancer is the most lethal gynaecological cancer due to late diagnosis and high level of recurrence (70% of patients).
During asynchronous complex firing, there was also a high level of recurrence (Fig. 8C,D), indicating that activity at this mature stage was highly structured.
There is no consensus on the surgical treatment of anal fistulas at present. 25 Management of complex anal fistulas remains a tremendous challenge because of the high level of recurrence and complications, depending of the type of fistula and choice of closure procedure.
However, scientists and clinicians alike have become intrigued with the finding that many patients who are diagnosed at an early stage, with small tumours and no evidence of regional lymph node metastases, can have a high level of recurrence when followed for greater than 10 to 15 years, in excess of 25%to30%0% [ 2, 3].
pEMR is already established as resulting in a higher level of recurrence, but the risk appears even larger with malignancy.
We found 595 (31.2%) recurrent mutations that can be collapsed onto 246 mtDNA positions, which is a 6.9-fold higher level of recurrence than expected by chance (p < 10−10).
The patterns of failure after curative resection in gastric cancer have been reported on many occasions (McNeer et al, 1951; Thomson and Robins, 1952; Wangensteen et al, 1954; Gunderson and Sosin, 1982; Wisbeck et al, 1986; Landry et al, 1990; Yoo et al, 2000), and these studies show high levels of locoregional recurrences after curative resection.
Venous thromboembolism (VTE) is a multifaceted disorder with high levels of morbidity, mortality, and recurrence worldwide [ 1].
Liver cancer is well characterized as a highly refractory cancer with high levels of tumor progression and recurrence for which there is no effective systemic therapy yet.
The same significant association between high levels of Maspin and early-recurrence and colorectal-specific survival was seen when applying the Dietmaier et al (2006) scoring system (P=0.040 and P=0.019; data not shown).
