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One such antiviral, brincidofovir (BCV, previously CMX001), has demonstrated high levels of efficacy against orthopoxviruses in animal models and is currently under clinical evaluation for prevention and treatment of diseases caused by cytomegaloviruses and adenoviruses.
This organism has several advantages, including low environmental toxicity due to the high specificity of B. sphaericus toxins, high levels of efficacy and environmental persistence, and the ability to overcome resistance developed against conventional insecticides used worldwide (Nielsen-LeRoux et al. 2001).
From the point of view of principles of pain physiology, the high levels of efficacy for the management of dynamic pain represents somewhat an interesting outcome –particularly when compared to the other standards of pain management, such as regional continuous techniques.
All these estimates assume high levels of efficacy and adherence to PrEP.
A further trial was undertaken in the same study site to compare different treatment regimens and high levels of efficacy against episodes of clinical malaria were observed with each treatment regimen [15].
Data from 3 large placebo-controlled clinical studies indicate that relatively high levels of efficacy (ranging from 60% to 90%) are seen in previously unvaccinated young children after a single dose of trivalent LAIV.
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Indeed, we believe that tSNS could be considered a first choice therapy in selected migraine populations due to the high level of efficacy and safety.
The combination of two mAbs expanded the breadth of protection with a high level of efficacy and safety associated with potential immune escape variants.
Residential programmes, while demonstrating a high level of efficacy in the short term, are especially cost prohibitive for many individuals.
Recently, mesenchymal stem cells (MSCs) have been extensively used in regenerative medicine and have achieved a high level of efficacy.
Interim trial results suggested that the vaccine could have a high level of efficacy in humans (3 ).
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