Sentence examples for high levels of constraint from inspiring English sources
We use data from three available bird genomes (chicken, turkey, and zebra finch) and find high levels of constraint: 24 43%.
We postulate that the extremely high levels of constraint on remaining photosynthetic genes may indicate an important function for these gene products in lipid biosynthesis rather than carbohydrate production through the Calvin Cycle.
These observations are consistent with a high level of constraint of the sequence variation, caused by strong purifying selection.
First, it appears that vertebrate pol γs show a high level of constraint, with little sequence and structural variability within the group.
In contrast, TashHN shows a high level of constraint and may function to alter a property of the host leukocyte that is fundamental to infection by both T. annulata and T. parva.
A larger historical N e for D. simulans than D. melanogaster predicts higher levels of constraint on synonymous and nonsynonymous sites in the former species.
The GOT1p1 paralog is the most conserved of the five paralogs with no evidence for segregating non-functional alleles (Table 2) and it has the highest levels of constraint as measured by ka/ks values (Table 1).
This may simply reflect differences in the overall importance of proteins for cellular functions, with more important proteins showing both higher levels of constraint on their amino acid sequence and stronger selection for codon usage.
The use of water from the river imposes an unusually high level of constraints on the design of the plant, due to possible extremes in temperature and the variable level of solids in suspension and other pollutants.
Chinese community residents had the lowest levels of knowledge of HIV, especially with regard to mother-to-child transmission, the most intent to avoid contact with people living with HIV and AIDS, and the highest levels of constraints to using services, including ineligibility for government healthcare and limited Thai language ability.
