In addition, lack of autophagy could result in the accumulation of damaged mitochondria and high-level reactive oxygen species generation and exposure, a stress condition that favor cancer cell growth, as they mainly rely on glycolysis for energy generation.
Mechanistic studies indicate that they can consume glutathione (GSH) and therefore induce high level of reactive oxygen species (ROS) in cancer cells, which further lead to cell apoptosis.
It is concluded that the limitations of the SMA 25 copolymer as a compatibilizer stem mainly from its high level of reactive functionality.
All patients of this group had high level of reactive anxiety (50,18±8,6, p<0,05), moderate level of depression and tendency to the decreasing of blood S concentration (205,72±21,62 ng/ml).
The soybean aphid may encounter a high level of reactive oxygen species (ROS) during feeding on the host plant (exogenous source) as well as deal with endogenous sources of ROS such as respiration [69], [70].
A high level of reactive oxygen species (ROS) is proposed to contribute to the pathophysiological mechanisms associated with various inflammatory skin disorders [ 1, 2].
CAMTA 3- knockout plants during developmental stages accumulates high level of reactive oxygen species (ROS), showed enhanced resistance towards fungal and bacterial pathogen by suppressing plant responses.
Considering the very high level of reactive oxygen species generation and low level of endogenous antioxidant in CY3-I neurons we investigated the effect of antioxidants on neuronal survival.
The mitochondrial genome is particularly susceptible to mutations because of the high level of reactive oxygen species generation in this organelle coupled with a low level of DNA repair.
7, 8, 9 High levels of reactive oxygen species and reactive nitrogen species are generated in COPD, resulting in induction of proinflammatory cytokines and chemokines, mucous hypersecretion, activation of proteases, and damage to cellular components.
