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In mouse models that lack adaptive immune cells, i.e., T and B cells, allergens can also induce significant AHR, a high level of type 2 cytokines, and increased numbers of ILC2s in the lung (Bartemes et al., 2012; Halim et al., 2012a).
In addition to the high level of type I collagen production, myofibroblasts are identified by their expression of alpha-smooth muscle actin [7], [9], [21], [22].
A large value of θML indicates a high level of Type I functional divergence, and vice versa.
Fibroblasts maintained on intact collagen synthesised a high level of type I procollagen and a low level of MMP-1.
pDCs have a dual role in defending viral infection, by secreting a high level of type I IFNs to inhibit viral replication directly and by initiating and tuning the specific adaptive immunity.
These variants include a potential causal SNP (rs2230926), which was suggested to reduce the ability of A20 to attenuate NF-κB signaling, resulting in a high level of type I interferon production [ 15, 33].
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The relatively high level of type-1 IGF receptors on NK cells suggests that IGF-I is likely to affect NK cells [ 93], but this has not been documented.
A cell that has a plasma cell-like morphology and produces high levels of type I interferons after exposure to viruses.
We identified MatrixFB-2 cells expressing high levels of type 1 collagens (Col1a1 and Col1a2), ECM components (Dpt, Vcan, and Eln), and Acta2.
Virus infection of mammalian cells induces the production of high levels of type I interferons (IFNα and β), cytokines that orchestrate antiviral innate and adaptive immunity.
Yeast have been engineered to express high levels of type I homotrimer and heterotrimer and type II and type III collagen.
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