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Notably, we find that unlike the high level of stimulation that we observed previously in the Drosophila system, stimulation of DNA synthesis catalyzed by human mtDNA polymerase is only moderate, and occurs over a narrow range of salt concentrations.
A high level of stimulation through the mER-α results in an interruption to breast cancer cell proliferation.
It has been hypothesized that the reduced ability of pDCs to produce IFN-α may be a consequence of the redistribution of the efficient pDCs into tissues [ 31] or of the exhaustion of circulating pDCs as a consequence of a high level of stimulation by persistent endogenous IFN-α inducing factors [ 13].
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People with this particular DNA need high levels of stimulation to feel alive and Everest represents this place where they can test themselves".
In the words of researchers Kari Knutson and Frank Farley, these people "prefer high levels of stimulation, complexity, and are distinguished by flexibility in thinking styles".
Depolarisation block describes the observation that neurons stop responding at high levels of stimulation despite being depolarised beyond the firing threshold.
Low levels of stimulation favouring the identification of negative pathway regulators and high levels of stimulation favouring the identification of positively acting factors.
Our analysis suggests that this imprecision results from a gradual saturation of receptor methylation sites at high levels of stimulation, which prevents full recovery of the pathway activity by violating the conditions required for precise adaptation.
Interviews with users revealed this preference stemmed from high levels of stimulation and enjoyment, derived from three TUI properties: physical interaction, rich feedback, and high levels of realism.
Our workplaces and classrooms are designed for extroverts and their need for high levels of stimulation — through classroom desks organized into pods, offices without walls, and constant group brainstorming sessions.
Results showed that stimulation of the AR pups reversed the effects of artificial rearing on apoptosis in a dose dependent manner; low and very high levels of stimulation were without effect whereas moderate levels of stimulation produced effects on apoptosis similar to effects seen in mother-reared controls.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com