Sentence examples for high level of platelet from inspiring English sources
The relatively high level of platelet adhesion after LP treatment and their morphology by SEM indicate that LP attracts blood elements such as proteins and platelets.
In contrast, relatively high level of platelet adhesion was noticed after LP treatment and platelet morphology indicated that some of them were activated.
The high level of platelet aggregation observed in patients with metastatic cancer is reflected by the EC50 value of each agonist, that is, the concentration of agonist which yields a response halfway between baseline and maximum aggregation.
The Global Utilisation of Strategies To prevent Occluded arteries IV (GUSTO IV) trial prospectively showed a high level of platelet inhibition achieved with the glycoprotein IIb/IIIa receptor inhibitor abciximab during 24 or 48 hours compared with placebo in patients with non-ST elevation acute coronary syndrome who were intended for initial medical management.
Here, we find that exceptionally high levels of platelet activation occur in the brain after neurotrauma, thereby providing in-principle support that platelet products may influence neuronal survival.
These findings support the rapid onset of antiplatelet effect and high levels of platelet inhibition observed with ticagrelor in clinical evaluation.
We demonstrate that patients with metastatic cancer are predisposed to high levels of platelet reactivity in response to low-dose agonist stimulation.
In agreement with these results, other investigators reported that high levels of platelet microaggregation were associated with adverse outcomes in patients with cardiovascular disease (16) and the ankle-brachial index in patients with peripheral arterial disease (17).
In accordance with previous reports in the literature, our platelets underwent activation upon contact with the cancer cell cultures and we also detected high levels of platelet activation in patient ascites (Additional file 2: Figure S2 and Additional file 3: Figure S3) [ 35].
The possibility that, despite very high levels of platelet inhibition achieved by ticagrelor, this treatment may not be sufficient for adequate protection against ischemic events in patients with DM has been raised previously, along with the possible requirement of other therapy, beyond the antiplatelet, antithrombin, or long-term anticoagulation one (3).
For example, high levels of platelet-derived growth factor-β receptor or SDF-1/CXCL12 and decreased caveolin-1 are associated with worse clinical outcome [ 50- 52].
